T Cell ELISPOT Testing Services

Let Our CRO Team Fast-Track Your T Cell ELISPOT

As pioneers in the ELISPOT arena, the Contract Research Laboratory Services team has more than a decade of proven expertise in the field of T cell ELISPOT.

Our CRO has developed and validated various customized T cell ELISPOT assays for pharmaceutical and biotechnology Clients—large and small—spanning diverse antigenic systems. We have successfully deployed such optimized, high-throughput assays for key clinical trials (Phase I, II, and III) and testing for translational and preclinical studies.

Let us help you get your project on the right footing. Reach out to our experienced immune monitoring team today.

t cell wells

Single, double, and multi-color T cell ELISPOT and FluoroSpot images

Our T cell ELISPOT assays can reliably utilize either fresh or cryopreserved PBMC

These immune assays range from single color ELISPOTs to novel, high-throughput multiplexed FluoroSpot assays that can be tailored to fit your specific project needs. Beyond clinical studies and the human system, our contract laboratory services has developed T cell ELISPOT assays for other species including non-human primates (NHP), rat, murine, and porcine systems, just to name a few.

We offer a wide range of single and multi-color T cell ELISPOT and FluoroSpot services to assess immunogenicity in test subjects. Our CRO offers both ready-to-go, kit-based T cell ELISPOT assay services and custom-designed assays to fit our Client’s specific project needs.

Our highly trained immune monitoring experts can help coordinate multiple clinical sites and can walk Clients through the complex aspects of T cell ELISPOT assay development, validation, deployment, and study logistics. Reach out to us to discuss your specific T cell ELISPOT project needs.

Our T cell ELISPOT/ImmunoSpot® method allows for complete characterization of immunogenicity:

  • Testing T cell-mediated immunity for pre-clinical and clinical specimens
  • High-throughput assay testing capabilities
  • Epitope mapping with overlapping peptides
  • Measurement of CD4+ and CD8+ T cell responses
  • Performing multiple assays using a limited number of cells/specimens
Based on assay configuration, CD4+ and CD8+ subsets and associated effector and memory populations can be assessed.

To further explore our extensive T cell assay services and related products, please refer to our T cell ImmunoSpot® kits and our CRO brochure.

As a key mission, the CRO specializes in developing and validating custom immune assays that are tailored to fit our Clients’ specific project needs.

Many such optimized assay services have helped our Pharma and Biotech Clients evaluate T cell immunogenicity in preclinical studies and clinical trials:

  • Immunotherapeutics (e.g., oncology, autoimmunity)
  • Vaccine studies (e.g., infectious diseases, cancer vaccines)
  • Transplantation (e.g., allo, MLR)
  • Gene therapies (e.g., AAV-9)
  • Safety assessments (e.g., ADA)

Our experienced immune monitoring team can help you reach your project milestones faster. For further information or a quote, please contact us today.

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