CTL’s TVA® Suite

The Target Cell Visualization Assay (TVA®) Suite is a high-throughput cell counting application designed to measure the lysis of fluorescence-labelled target cells in a 96-well or Terasaki plate formats. Antibody-dependent cell-mediated cytotoxicity (ADCC), Natural Killer (NK)- or CD8+ T cell-mediated lysis can be measured this way. TVA was proven to have equal sensitivity with the traditional Chromium 51-release assays [ref], however without involving radioactivity. In a multi-color variant of TVA, the lysis of several target cells, each loaded with different dies, can be tested simultaneously. The TVA®-Suite enables streamlined work flow from planning the experiment to automated generation of graphs, as shown below. Learn more about the TVA Assay, and about the regulatory compliance of the TVA® Software.